3 Approved GMOs Connected to Organ Damage

15th January 2012

By Rady Anandafoodfreedom.wordpress.com

In what is being described as the first ever and most comprehensive study of the effects of genetically modified foods on mammalian health, researchers have linked organ damage with consumption of Monsanto’s GM maize.

Three varieties of Monsanto’s GM corn – Mon 863, insecticide-producing Mon 810, and Roundup ® herbicide-absorbing NK 603 – were approved for consumption by US, European and several other national food safety authorities. The data used for this approval, ironically, is the same data that independent researchers studied to make the organ damage link.

The Committee of Independent Research and Information on Genetic Engineering (CRIIGEN) and Universities of Caen and Rouen obtained Monsanto’s confidential raw data of its 2002 feeding trials on rats after a European court made it public in 2005.

The data “clearly underlines adverse impacts on kidneys and liver, the dietary detoxifying organs, as well as different levels of damages to heart, adrenal glands, spleen and haematopoietic system,” reported Gilles-Eric Séralini, a molecular biologist at the University of Caen.

Although different levels of adverse impact on vital organs were noticed between the three GMOs, the 2009 research shows specific effects associated with consumption of each, differentiated by sex and dose.

Their December 2009 study appears in the International Journal of Biological Sciences (IJBS). This latest study conforms with a 2007 analysis by CRIIGEN on Mon 863, published in Environmental Contamination and Toxicology, using the same data.

Monsanto rejected the 2007 conclusions, stating:

“The analyses conducted by these authors are not consistent with what has been traditionally accepted for use by regulatory toxicologists for analysis of rat toxicology data.”

[Also see Doull J, Gaylor D, Greim HA, et al. “Report of an expert panel on the reanalysis by Séralini et al. (2007) of a 90-day study conducted by Monsanto in support of the safety of a genetically modified corn variety (MON 863).” Food Chem Toxicol. 2007; 45:2073-2085.]

In an email to me, Séralini explained that their study goes beyond Monsanto’s analysis by exploring the sex-differentiated health effects on mammals, which Doull, et al. ignored:

“Our study contradicts Monsanto conclusions because Monsanto systematically neglects significant health effects in mammals that are different in males and females eating GMOs, or not proportional to the dose. This is a very serious mistake, dramatic for public health. This is the major conclusion revealed by our work, the only careful reanalysis of Monsanto crude statistical data.”

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Other problems with Monsanto’s conclusions

When testing for drug or pesticide safety, the standard protocol uses three mammalian species. The subject studies only used rats, yet won GMO approval in more than a dozen nations.

Chronic problems are rarely discovered in 90 days; most often such tests run for up to two years. Tests “lasting longer than three months give more chances to reveal metabolic, nervous, immune, hormonal or cancer diseases,” wrote Seralini, et al. in their Doull rebuttal. [See “How Subchronic and Chronic Health Effects can be Neglected for GMOs, Pesticides or Chemicals.” IJBS; 2009; 5(5):438-443.]

Further, Monsanto’s analysis compared unrelated feeding groups, muddying the results. The June 2009 rebuttal explains, “In order to isolate the effect of the GM transformation process from other variables, it is only valid to compare the GMO … with its isogenic non-GM equivalent.”

The researchers conclude that the raw data from all three GMO studies reveal novel pesticide residues will be present in food and feed and may pose grave health risks to those consuming them.

They have called for “an immediate ban on the import and cultivation of these GMOs and strongly recommend additional long-term (up to two years) and multi-generational animal feeding studies on at least three species to provide true scientifically valid data on the acute and chronic toxic effects of GM crops, feed and foods.”

Human health, of course, is of primary import to us, but ecological effects are also in play. Ninety-nine percent of GMO crops either tolerate or produce insecticide. This may be the reason we see bee colony collapse disorder and massive butterfly deaths. If GMOs are wiping out Earth’s pollinators, they are far more disastrous than the threat they pose to humans and other mammals.

Further Reading

Genetic Roulette: The Documented Health Risks of Genetically Engineered Foods, Jeffrey M. Smith

Failure to Yield: Evaluating the Performance of Genetically Engineered Crops, Union of Concerned Scientists

Impacts of Genetically Engineered Crops on Pesticide Use: The First Thirteen Years, The Organic Center

About the Author

Holding a B.S. in Natural Resources from The Ohio State University’s School of Agriculture, Rady Ananda’s work has appeared in several online and print publications. Using years of editorial experience and web publishing, Rady now promotes the ideas and work of a select group of quality writers and artists at Food Freedom and COTO Report.


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  • pseudotsuga

    Now Monsanto is genetically manipulating honeybees, and patenting the process!

  • CM
    • RichieG

      There’s always two sides to any story. However, this issue merely becomes muddier and muddier, I’m not sure I trust Monsanto in the end even if Seralini et al appear to be merely rocking the boat..

  • Thank you! I LOVE the title of this article, “Wake up World.” Why is so hard to educate people on the damage they themselves are causing? Ugh…”wake up world”

  • Evelyn Vincent

    Monsanto has been wheedling their way into the White House since the days of Bush Sr. We paid no attention to it, now look where we are. We have a monster on our hands. Despite the warnings and proper studies done over previous years, we have done nothing to stop Monsanto. We’ve also allowed our government, and companies, to ‘convince’ us that something we question as being not so bad. In the process, we’ve ended up with this… this great evil that can and will change the face of all life on this planet.
    For the past 10 years, I have spent countless hours of my life trying to help others realize what’s going on with Monsanto and to do something about it. Stop buying products that contain GMO ingredients, to not buy their produce on store shelves, to stand up and demand something better, stand up and get Monsanto out of our governments policy decision making. Many thought what I was saying was extreme and it couldn’t happen.
    Here we are… and even if we were able to stop GM seed/food we also have to realize that Monsanto is NOT going to simply roll-over and play dead. They would simply do another manipulative thing because they can’t stop doing what they’re doing at this point, there’s too much money and control at stake (for them and those involved). We’ve made a HUGE mistake, one that future generations will be paying for dearly.
    They have an agenda, one that is now deeply rooted, they’re not going to turn around and say, “oh, good people of the world, you’re right… we’ll stop controlling you and the future of food and now we’ll be the model of ecology and good health for you and your children.” That’s not going to happen.
    Monsanto is so deeply imbedded in our government right now and have so much at stake that I cannot imagine that they have the desire to do a 180. I think we all need to wake up to that fact too… and, what can we do with that against us.
    This isn’t good, we’ve waited too long, it’s become more complicated. I don’t know what the answer is anymore, I don’t know what we can do that would actually completely stop Monsanto and what we could do to prevent them from turning around and doing something else that is equally as wrong and bad. I don’t know if there is an answer or a solution at this point.
    Genetically Modified (GM) canola has been found growing along roadsides, I wrote a post on it at my blog last October http://sacredhabitats.com/2011/10/12/genetically-modified-gm-canola-found-growing-along-roadsides/ Anyone who knows anything about plants knew that was only a matter of time, not a matter of ‘if.’
    Percy Schmeiser, a Canadian canola farmer, fought Monsanto for years because the seed he and his family had been saving for decades became contaminated with GM canola seed that apparently blew off of neighboring farm vehicles, neighbors who grew Monsanto’s GM canola.
    The fact is, we’ve let a monster into each and every kitchen. We’ve let a monster lose on our beautiful land. We’ve let this monster control us and our health.
    What we have on our hands here is far more than a ‘wake-up-call,’ the wake-up came over 20 years ago, and no one listened.
    What are we going to do about it now? What are you willing to do about it?
    How far will you go to protect your health (mental and physical), the health of your children, and the health of our planet and all living species on it?
    What are you willing to do when Monsanto doesn’t back-down?
    I think these are the real questions we need to ask ourselves. We need to spend some time searching our souls and come together on what needs to be done to stop things like this from occurring from this point onward.
    Apologies if this sounds pessimistic, it is factual and does state where we are right now, minus any sugar-coating.

  • Erin

    how do we know which corn is GMO?