Monsanto’s Roundup Herbicide Toxic To Life In Parts Per Billion Range

By  Sayer Ji

Contributing Writer for  Wake Up World

New research on the DNA-damaging effects of the popular herbicide known as Roundup ® indicates that it can do significant harm to fish even after short-term, environmentally low concentration exposures in the  parts per billion range  (μg /L).[i]

Published this month (July, 2012) in the journal  Environmental   Monitoring and Assessments  researchers set out to evaluate the  genotoxic effects that the herbicide Roundup ®, and its primary ingredient glyphosate, can have on a species of catfish known as Corydorasa paleatus.  When exposed to minute concentrations of Roundup (at a concentration of 6.67  Î¼g/L, corresponding to 3.20  Î¼g/L glyphosate) for 3,6 and 9 days, the following effects were observed:  “[T]he comet assay showed a high rate of DNA damage in group exposed to Roundup( ®) for all treatment times, both for blood and hepatic cells.” The researchers summarized their findings:

“We conclude that for the low concentration used in this research, the herbicide shows potential genotoxic effects. Future research will be important in evaluating the effects of this substance, whose presence in the environment is ever-increasing.”


First, it is very important to understand how low a μg /L or parts per billion concentration is.  One way to visualize it is to think of one drop in one billion drops of water, or what amounts to one drop of water in an entire swimming pool.[ii]

Owing to the fact that glyphosate is now a ubiquitous contaminant in our environment, having been  found in most U.S. air and rain samples tested,[iii]  as well as being measured beyond the limit of quantification (higher than 2.5 ug/L) in 41% of 140 groundwater samples collected from Catalonia Spain, this new finding has profound implications for environmental and human health alike. With over 88,000 tons of the stuff used in the US in 2007,  according to the USGS, and with an ever-expanding volume being applied to increasingly glyphosate-resistant GM crops, the problem of exposure is only going to get worse in the future – that is, if we continue to support the growth of glyphosate-dependent GM crop industries.

Monsanto, the originator of glyphosate and its most popular branded formulation, Roundup ®, once marketed their herbicide “as safe as table salt,” and claimed it was “highly biodegradable.” These claims have now been disproved. Like  Agent Orange, another Monsanto co-creation (along with Dow Chemicals, and several other government contractors), this herbicide exhibits a broad range of  biocidal (life-killing) properties. (Note: the concept of a “weedkiller” is absurd. These chemicals do not selectively kill only targeted plants. Also, a “weed” is simply a plant whose virtues we have yet discovered [Emerson], or which is encroaching on a plant we favor).

Some of the ways in which glyphosate formulations have been experimentally confirmed to disrupt, mutate, alter or kill are as follows

Of all the adverse health effects listed here, the genotoxicity (DNA-damaging) of glyphosate is the most concerning, and the most consistently supported by the evidence. We have 16 studies on our database substantiating this connection alone, and these studies involve human cell line and animal research as well. DNA-damage has, in fact, been considered the primary factor in carcinogenesis for well over half a century, that is, ever since the multi-mutation theory on cancer was first conceived by Carl O. Nordling in 1953.

If, as accumulating research indicates, the world’s most popular herbicide is contributing to cancer, and that all GM-produced food which is engineered “Roundup Ready” and therefore saturated with glyphosate residues is also a cancer risk, the increasingly global food hegemony of biotech corporations such as Monsanto will be halted in its tracks. Could the growing recognition that glyphosate-based herbicides are contributing to cancer be one reason why Monsanto has been ramping up its funding of privately contracted published research explicitly refuting the accumulating glyphosate/Roundup-cancer connection?

While the pseudo-scientific technocratic dictatorship holds the “weight of the evidence” toxicological risk assessment standard against exposed populations, compelling  them  to prove that the harms of agrochemicals to human and environmental health outweigh their purported benefits, those of us with a modicum of common sense, and even a layman’s understanding of the precautionary principle, i.e. if there is preliminary evidence a chemical to which we are exposed is unsafe, regulate it accordingly, can vote with our forks and dollars and stop spending our money on GM-containing and/or GM-assocciated foods and products. Also, support the  California GMO labeling initiative.

For additional research and articles visit our  Health Guide: GMO Research

Article Sources

[i]  Nédia de Castilhos Ghisi, Marta Margarete Cestari   Genotoxic effects of the herbicide Roundup( ®) in the fish Corydoras paleatus (Jenyns 1842) after short-term, environmentally low concentration exposure. Environ Monit Assess. 2012 Jul 22. Epub 2012 Jul 22. PMID:  22821326

[ii] [EPA sponsored], pdf.  Understanding Units of Measurement

[iii]  Feng-chih Chang, Matt F Simcik, Paul D Capel. Occurrence and fate of the herbicide glyphosate and its degradate aminomethylphosphonic acid in the atmosphere. Environ Toxicol Chem. 2011 Mar;30(3):548-55. Epub 2011 Jan 19. PMID:  21128261

About the Author


Sayer Ji is the founder and editor-in-chief of and co-author of the book  The Cancer Killers: The Cause Is The Cure  with New York Times best-seller Dr. Ben Lerner and Dr. Charles Majors. His writings and research have been published in the Wellbeing Journal, the Journal of Gluten Sensitivity, and have been featured on,,,, and


If you've ever found value in our articles, we'd greatly appreciate your support by purchasing Mindful Meditation Techniques for Kids - A Practical Guide for Adults to Empower Kids with the Gift of Inner Peace and Resilience for Life.

In the spirit of mindfulness, we encourage you to choose the paperback version. Delve into its pages away from screen glare and notifications, allowing yourself to fully immerse in the transformative practices within. The physical book enriches the learning process and serves as a tangible commitment to mindfulness, easily shared among family and friends.

Over the past few years, Wake Up World has faced significant online censorship, impacting our financial ability to stay online. Instead of soliciting donations, we're exploring win-win solutions with our readers to remain financially viable. Moving into book publishing, we hope to secure ongoing funds to continue our mission. With over 8,500 articles published in the past 13 years, we are committed to keeping our content free and accessible to everyone, without resorting to a paywall.