Scientists Officially Link Processed Foods To Autoimmune Disease

Scientists Officially Link Processed Foods To Autoimmune Disease

By April McCarthy

Guest Writer for Wake Up World

The modern diet of processed foods, takeaways and microwave meals could be to blame for a sharp increase in autoimmune diseases such as multiple sclerosis, alopecia, asthma and eczema.

A team of scientists from Yale University in the U.S and the University of Erlangen-Nuremberg, in Germany, say junk food diets could be partly to blame. “This study is the first to indicate that excess refined and processed salt may be one of the environmental factors driving the increased incidence of autoimmune diseases”, they said.

Junk foods at fast food restaurants as well as processed foods at grocery retailers represent the largest sources of sodium intake from refined salts.

Salt and Processed Food

The Canadian Medical Association Journal  sent out an international team of researchers  to compare the salt content of 2,124 items from fast food establishments such as Burger King, Domino’s Pizza, Kentucky Fried Chicken, McDonald’s, Pizza Hut and Subway. They found that the average salt content varied between companies and between the same products sold in different countries.

U.S. fast foods are often more than twice as salt-laden as those of other countries. While government-led public health campaigns and legislation efforts have reduced refined salt levels in many countries, the U.S. government has been reluctant to press the issue. That’s left fast-food companies free to go salt crazy, says Norm Campbell, M.D., one of the study authors and a blood-pressure specialist at the University of Calgary.

Many low-fat foods rely on salt – and lots of it – for their flavor. One packet of KFC’s Marzetti Light Italian Dressing might only have 15 calories and 0.5 grams fat, but it also has 510 mg sodium – about 1.5 times as much as one Original Recipe chicken drumstick. (Feel like you’re having too much of a good thing? You probably are).

Bread is the No. 1 source of refined salt consumption in the American diet, according to the Centers for Disease Control and Prevention. Just one 6-inch Roasted Garlic loaf from Subway – just the bread, no meat, no cheeses, no nothing – has 1,260 mg sodium, about as much as 14 strips of bacon.

How Refined Salt Causes Autoimmune Disease

The team from Yale University studied the role of T helper cells in the body. These activate and ‘help’ other cells to fight dangerous pathogens such as bacteria or viruses and battle infections.

Previous research suggests that a subset of these cells – known as Th17 cells – also play an important role in the development of autoimmune diseases.

In the latest study, scientists discovered that exposing these cells in a lab to a table salt solution made them act more “aggressively”.  They found that mice fed a diet high in refined salts saw a dramatic increase in the number of Th17 cells in their nervous systems that promoted inflammation.  They were also more likely to develop a severe form of a disease associated with multiple sclerosis in humans.

The scientists then conducted a closer examination of these effects at a molecular level.  Laboratory tests revealed that salt exposure increased the levels of cytokines released by Th17 cells 10 times more than usual. Cytokines are proteins used to pass messages between cells.

Study co-author Ralf Linker, from the University of Erlangen-Nuremberg, said:

“These findings are an important contribution to the understanding of multiple sclerosis and may offer new targets for a better treatment of the disease, for which at present there is no cure.”

Multiple Sclerosis  develops when the immune system mistakes the myelin that surrounds the nerve fibres in the brain and spinal cord for a foreign body.  It strips the myelin off the nerves fibres, which disrupts messages passed between the brain and body causing problems with speech, vision and balance.

Another of the study’s authors, Professor David Hafler from Yale University, said that nature had clearly not intended for the immune system to attack its host body, so he expected that an external factor was playing a part.  He said:

“These are not diseases of bad genes alone or diseases caused by the environment, but diseases of a bad interaction between genes and the environment.

“Humans were genetically selected for conditions in sub-Saharan Africa, where there was no salt. It’s one of the reasons that having a particular gene may make  African Americans much more sensitive to salt.

“Today, Western diets all have high salt content and that has led to increase in hypertension and perhaps autoimmune disease as well.”

The team next plan to study the role that Th17 cells play in autoimmune conditions that affect the skin. The said:

“It would be interesting to find out if patients with psoriasis can alleviate their symptoms by reducing their salt intake, however, the development of autoimmune diseases is a very complex process which depends on many genetic and environmental factors.”

Stick to Good Salts

Refined, processed and bleached salts are the problem. Salt is critical to our health and is the most readily available nonmetallic mineral in the world. Our bodies are not designed to processed refined sodium chloride since it has no nutritional value. However, when a salt is filled with dozens of minerals such as in rose-coloured crystals of Himalayan rock salt or the grey texture of Celtic salt, our bodies benefit tremendously for their incorporation into our diet.

Says  Dr. Barbara Hendel, researcher and co-author of Water & Salt, The Essence of Life:

“These mineral salts are identical to the elements from  which our bodies have been built and were originally found in the primal ocean from where life originated. We have salty tears and salty perspiration. The chemical and mineral composition of our blood and body fluids are similar to sea water. From the beginning of life, as unborn babies, we are encased in a sack of salty fluid.

“In water, salt dissolves into mineral ions.  These conduct electrical nerve impulses that drive muscle movement and thought processes. Just the simple act of drinking a glass of water requires millions of instructions that come from mineral ions. They’re also needed to balance PH levels in the body.”

Mineral salts, explains Dr. Handel, are healthy because they give your body the variety of mineral ions needed to balance its functions, remain healthy and heal. These healing properties have long been recognised in central Europe. At Wieliczka in Poland, a hospital has been carved in a salt mountain. Asthmatics and patients with lung disease and allergies find that breathing air in the saline underground chambers helps improve symptoms in 90 per cent of cases.

Dr. Hendel believes too few minerals, rather than too much salt, may be to blame for health problems. It’s a view that is echoed by other academics such as David McCarron, of Oregon Health Sciences University in the US.  He says salt has always been part of the human diet, but what has changed is the mineral content of our food. Instead of eating food high in minerals, such as nuts, fruit and vegetables, people are filling themselves up with “mineral empty” processed food and fizzy drinks.

Study Source:

This is the result of a study conducted by Dr. Markus Kleinewietfeld, Prof. David Hafler (both Yale University, New Haven and the Broad Institute of the Massachusetts Institute of Technology, MIT, and Harvard University, USA), PD Dr. Ralf Linker (Dept. of Neurology, University Hospital Erlangen), Professor Jens Titze (Vanderbilt University and Friedrich-Alexander-Universitat Erlangen-Nurnberg, FAU, University of Erlangen-Nuremberg) and Professor Dominik N. Muller (Experimental and Clinical Research Center, ECRC, a joint cooperation between the Max-Delbruck Center for Molecular Medicine, MDC, Berlin, and the Charite — Universitatsmedizin Berlin and FAU) (Nature, doi:*.  Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells.

Previous articles by April:

About the author:  

April McCarthy  is a community journalist playing an active role reporting and analyzing world events to advance our health and eco-friendly initiatives.

This article was reposted with permission from


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  • Beth Gordon

    Sorry..although I do believe that diet and lifestyle exasperate Autoimmune diseases I don’t think they actually cause them. My first Autoimmune disease started when I was about 3 or 4 (according to my parents) At that time Britain was still recovering from the war so sugar, meat etc, were still rationed. My dad was a farm laborour and our milk came directly from the cow, our meat was slaughtered in the back garden, eggs came from our chickens and all the veggies our family ate came from our garden. About the only things my mum bought from the stores was Tea and soap products. I have several Cousins and Aunts with the same disease although most of them were in their teens and 20’s when they got diagnosed. There was no processed foods in my diet, very little meat and most of my time was spent playing outside (we had no television so were def not couch potatoes) When people make these claims that autoimmune diseases come from lifestyle or diet you are in all reality saying that it is the sufferers own fault that they are ill. Sorry for being long winded but it is akin to saying that people suffering from depression should just “snap” out of it. Lifestyle and diet changes can and do alleviate some of the symptoms but they are NOT the cause of the illness

    • Tree

      Food does cause autoimmunity. Genetics load the gun environment pulls the trigger. Food and chemicals change gene expression. Food is information to our body. The ppl who don’t think this is possible are foolish and brainwashed from mainstream media. We would never put bad fuel in a car and expect it to work, why would we put it in ourselves. All food that’s not life food is dead food. Beth you were still esting plenty of dead unnatural food. Life begets life and dead begets dead. No other creature on the planet eats cooked food. Wake up people.

  • Betsy

    This article does a disservice to those of us with autoimmune diseases. Sodium chloride does, in fact, have a nutritional value. Sodium is necessary for muscle and nerve function, not to mention it helps regulate hydration. The Yale study indicated that excessive amounts of salt may be a factor in autoimmune disease. Lastly, to have expert testimony on Himalayan rock salt from someone who sells Himalayan rock salt as Dr. Barbara Handel does is a conflict of interest. It is hard to take advice from someone who stands to benefit financially from it.

    • Wake Up World

      Just to be clear, the article stated “processed refined sodium chloride” (Table Salt) having no nutritional value.

  • Janna

    Beth Gordon, you make some good points there. I think that you are right. I also think that with the explosion of the autoimmune attacking our systems that with a lot of people diet would have to be taken into consideration. I know people that didn’t come down with an auto immune disease until much later in life. These people normally do not eat healthy at all. Also, with all the environmental factors.. i.e. population explosion, pollution, gmo’s, fast food, hidden chemicals in our food, chemicals sprayed, etc. that this has to have a huge effect on humankind.

  • Elle Matthews

    For those of us that are the 1st in our families to have any type of the “New” overwhelming diseases, as Ulcerative Colitis or Crones Disease it may very well be that in some cases “Genetic” can mean sitting around the same table as Grandma, Gramps, cousins, auntie, Uncle, Mom & Dad. All eating the same polluted food, mercury fish, hormonal meat, toxic sprayed vegis and more….How many people in the world, everywhere, are lactose intolerant? We try to eat well and have all the right food groups, and take a vitamin for this or that. But….almost everything we buy in the store is toxic. What to do? The best we can. Heredity does exist but add poison and you have a very serious combo. Try to live well, and enjoy every day regardless of our markets.